BDBM50197129 CHEMBL387309::N-[1-[(2-fluoro-4-methoxybenzyl)methyl]piperidin-4-yl]-7-fluoro-4-oxo-4H-chromene-2-carboxamide

SMILES COc1ccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)c(F)c1

InChI Key InChIKey=RASPHJGGIPBIMT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197129   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197129(N-[1-[(2-fluoro-4-methoxybenzyl)methyl]piperidin-4...)
Affinity DataIC50: 14.7nMAssay Description:Displacement of [3H]dofetilide from hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197129(N-[1-[(2-fluoro-4-methoxybenzyl)methyl]piperidin-4...)
Affinity DataIC50: 53nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197129(N-[1-[(2-fluoro-4-methoxybenzyl)methyl]piperidin-4...)
Affinity DataIC50: 411nMAssay Description:Antagonist activity at MCHr1 assessed as inhibition of MCH-mediated calcium ion release in intact IMR32 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed