BDBM50197507 (S)-4-methoxy-2-{1-[(1R,2S)-2-(4-methoxy-phenyl)-cyclopropylcarbamoyl]-cyclopentylmethyl}-butyric acid::CHEMBL389061

SMILES COCC[C@H](CC1(CCCC1)C(=O)N[C@@H]1C[C@H]1c1ccc(OC)cc1)C(O)=O

InChI Key InChIKey=WAFMGROHMCCENJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197507   

TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50197507((S)-4-methoxy-2-{1-[(1R,2S)-2-(4-methoxy-phenyl)-c...)
Affinity DataIC50: 6.10nMpH: 7.0Assay Description:Inhibition of human kidney NEP at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50197507((S)-4-methoxy-2-{1-[(1R,2S)-2-(4-methoxy-phenyl)-c...)
Affinity DataIC50: 13.8nMpH: 7.4Assay Description:Inhibition of human kidney NEP at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed