BDBM50197519 (S)-2-{1-[3-(4-fluoro-phenyl)-propylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyric acid::CHEMBL224670

SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(F)cc1)C(O)=O

InChI Key InChIKey=MPWCDZKWKGSZCI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197519   

TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50197519((S)-2-{1-[3-(4-fluoro-phenyl)-propylcarbamoyl]-cyc...)
Affinity DataIC50: 4.60nMpH: 7.0Assay Description:Inhibition of human kidney NEP at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50197519((S)-2-{1-[3-(4-fluoro-phenyl)-propylcarbamoyl]-cyc...)
Affinity DataIC50: 12.6nMpH: 7.4Assay Description:Inhibition of human kidney NEP at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed