BDBM50197898 6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyclopent-1-enyl)picolinic acid::6-(2-(5-chloro-2-(2,4-difluorobenzyloxy)phenyl)cyclopent-1-enyl)picolinic acid::CHEMBL234940

SMILES OC(=O)c1cccc(n1)C1=C(CCC1)c1cc(Cl)ccc1OCc1ccc(F)cc1F

InChI Key InChIKey=PFODPHDNBFSMOX-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50197898   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50197898(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50197898(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)
Affinity DataIC50:  8.90E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50197898(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50197898(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)
Affinity DataIC50:  2.51nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50197898(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50197898(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50197898(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [3H]PGE2 from EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50197898(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed