BDBM50197966 CHEMBL3959869

SMILES C/C1=C\C[C@]2(C(C)C)CC[C@@](C)(O2)[C@@H](OC(=O)c2ccccc2)CC/C(C)=C/CC1

InChI Key InChIKey=AKGLTDYPASAOIS-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197966   

TargetHeat sensitive channel TRPV3(Rat)
University of Eastern Piedmont

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197966BDBM50197966(CHEMBL3959869)
Affinity DataEC50:  4.40E+3nMAssay Description:Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197966BDBM50197966(CHEMBL3959869)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetHeat sensitive channel TRPV3(Rat)
University of Eastern Piedmont

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197966BDBM50197966(CHEMBL3959869)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed