BDBM50198284 1-((1H-indol-3-yl)methyl)-4-(3,4-dichlorophenyl)piperidin-4-ol::CHEMBL246637

SMILES OC1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=YZIXUQBOLGXTJS-UHFFFAOYSA-N

Data  5 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50198284   

TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50198284(1-((1H-indol-3-yl)methyl)-4-(3,4-dichlorophenyl)pi...)
Affinity DataKi:  6.90nMAssay Description:Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50198284(1-((1H-indol-3-yl)methyl)-4-(3,4-dichlorophenyl)pi...)
Affinity DataKi:  6.90nMAssay Description:Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198284(1-((1H-indol-3-yl)methyl)-4-(3,4-dichlorophenyl)pi...)
Affinity DataKi:  111nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198284(1-((1H-indol-3-yl)methyl)-4-(3,4-dichlorophenyl)pi...)
Affinity DataKi:  111nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198284(1-((1H-indol-3-yl)methyl)-4-(3,4-dichlorophenyl)pi...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]IABN from human dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198284(1-((1H-indol-3-yl)methyl)-4-(3,4-dichlorophenyl)pi...)
Affinity DataEC50:  41.5nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHO cells assessed as inhibition of quinpirole stimulated mitogenesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50198284(1-((1H-indol-3-yl)methyl)-4-(3,4-dichlorophenyl)pi...)
Affinity DataEC50:  15.3nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in CHO cells assessed as inhibition of quinpirole stimulated mitogenesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed