BDBM50198570 (6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(3-chloro-phenyl)-2,3,6,7,12,12a-hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione::CHEMBL394963

SMILES Clc1cccc(c1)N1CC(=O)N2[C@H](Cc3c([nH]c4ccccc34)[C@H]2c2ccc3OCOc3c2)C1=O

InChI Key InChIKey=GZIVRZHZEBIZEH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198570   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Inserm U761 Biostructures and Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198570((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(3-chloro-phen...)
Affinity DataIC50: 141nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed