BDBM50198595 1-(3-(4-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yloxy)propyl)piperidine-4-carbonitrile::CHEMBL394801

SMILES COc1ccc(cc1)C1CN(C)Cc2cc(OCCCN3CCC(CC3)C#N)ccc12

InChI Key InChIKey=DTYOTXLNOUBXKR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50198595   

TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50198595(1-(3-(4-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahy...)
Affinity DataKi:  5.30nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50198595(1-(3-(4-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahy...)
Affinity DataKi:  5.30nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50198595(1-(3-(4-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahy...)
Affinity DataKi:  7.40nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed