BDBM50198827 7-(2,6-dimethylphenyl)-N5-methyl-N3-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)benzo[e][1,2,4]triazine-3,5-diamine::CHEMBL230830::US8481536, 503

SMILES CNc1cc(cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12)-c1c(C)cccc1C

InChI Key InChIKey=VPQXLOMEHCTHBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198827   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Targegen

Curated by ChEMBL
LigandPNGBDBM50198827(US8481536, 503 | CHEMBL230830 | 7-(2,6-dimethylphe...)
Affinity DataIC50: 10nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Targegen

Curated by ChEMBL
LigandPNGBDBM50198827(US8481536, 503 | CHEMBL230830 | 7-(2,6-dimethylphe...)
Affinity DataIC50: 10.6nMT: 2°CAssay Description:Recombinant human c-Src or Yes (28 ng/well, Panvera/Invitrogen, Madison Wis.), ATP (3 μM), a tyrosine kinase substrate (PTK2, 250 μM, Promega C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent