BDBM50199094 CHEMBL3948027

SMILES CC(=O)c1ccc(OCc2ccc(F)cc2)cc1O

InChI Key InChIKey=RFHGZHJAFVVQFU-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50199094   

TargetAmine oxidase [flavin-containing] B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50199094BDBM50199094(CHEMBL3948027)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human MAO-B using kynuramine as substrate assessed as decrease in 4-hydroxyquinoline production incubated for 20 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50199094BDBM50199094(CHEMBL3948027)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate assessed as decrease in H2O2 production incubated for 15 mins by fluorimetric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50199094BDBM50199094(CHEMBL3948027)
Affinity DataIC50: 58nMAssay Description:Inhibition of human recombinant MAO-B incubated for 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
Beijing Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50199094BDBM50199094(CHEMBL3948027)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of amyloid beta 1 to 42 (unknown origin) aggregation assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Beijing Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50199094BDBM50199094(CHEMBL3948027)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MAO-A (unknown origin) using tyramine hydrochloride as substrate preincubated with compound for 90 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Beijing Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50199094BDBM50199094(CHEMBL3948027)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant human MAO-A using kynuramine as substrate assessed as decrease in 4-hydroxyquinoline production incubated for 20 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Beijing Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50199094BDBM50199094(CHEMBL3948027)
Affinity DataIC50: 4.34E+4nMAssay Description:Inhibition of recombinant human MAO-A using p-tyramine as substrate assessed as decrease in H2O2 production incubated for 15 mins by fluorimetric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed