BDBM50199531 1-[16-methyl-5-oxo-6,14-diazatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,16-trien-14-yl]-2-(4-{2-[16-methyl-5-oxo-6,14-diazatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,16-trien-14-yl]-2-oxoethyl}hexahydro-1-pyrazinyl)-1-ethanone::CHEMBL244870::N,N'-bis(1-oxo-8,15-didehydrolycodinocarbonylmethyl)-piperazine

SMILES CC1=C[C@H]2Cc3[nH]c(=O)ccc3[C@@]3(C1)[C@@H]2CCCN3C(=O)CN1CCN(CC(=O)N2CCC[C@@H]3[C@@H]4Cc5[nH]c(=O)ccc5[C@]23CC(C)=C4)CC1

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50199531   

TargetAcetylcholinesterase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50199531(N,N'-bis(1-oxo-8,15-didehydrolycodinocarbonylmethy...)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibitory concentration against acetylcholinesterase from rat cortex homogenate by ellman method was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50199531(N,N'-bis(1-oxo-8,15-didehydrolycodinocarbonylmethy...)
Affinity DataIC50: 1.17E+3nMpH: 5.0Assay Description:Inhibition of AChE in rat cortex at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50199531(N,N'-bis(1-oxo-8,15-didehydrolycodinocarbonylmethy...)
Affinity DataIC50: 1.84E+5nMAssay Description:Inhibition of BuChE in rat serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50199531(N,N'-bis(1-oxo-8,15-didehydrolycodinocarbonylmethy...)
Affinity DataIC50: 1.84E+5nMAssay Description:Inhibitory concentration against butyrylcholinesterase from rat serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed