BDBM502 2-({4-[bis(3-hydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)methyl]phenyl}(3-hydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)methyl)-3-hydroxy-1,4-dihydronaphthalene-1,4-dione::CHEMBL66033::Cancer Chemotherapy National Service Center (CCNSC) compound 117027::NSC 117027
SMILES Oc1c(O)c2ccccc2c(O)c1C(=C1C(=O)C(=O)c2ccccc2C1=O)c1ccc(cc1)C(C1C(=O)C(=O)c2ccccc2C1=O)C1C(=O)C(=O)c2ccccc2C1=O
InChI Key InChIKey=UPELKACGIHBTIT-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 502
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health
National Institutes of Health
Affinity DataIC50: 750nMpH: 6.5 T: 37°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibitory activity against HIV-1 Protease.More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibitory activity against topoisomerase I.More data for this Ligand-Target Pair