BDBM50200590 CHEMBL238602::N-allyl-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-2-oxo-2,3-dihydrobenzimidazol-1-yl)-acetamide

SMILES COc1ccc(C)c(OC(CCN2CCC(CC2)n2c3ccccc3n(CC(=O)NCC=C)c2=O)C(C)C)c1

InChI Key InChIKey=QNDUBQQKEYXAEX-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50200590   

TargetNociceptin receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200590(N-allyl-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200590(N-allyl-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-...)
Affinity DataIC50: 166nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200590(N-allyl-2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-...)
Affinity DataKi:  199nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed