BDBM50200595 (+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one::(-)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one::1-(1-(3-(5-methoxy-2-methylphenoxy)-4-methylpentyl)piperidin-4-yl)-3-(2-methoxyethyl)-1H-benzo[d]imidazol-2(3H)-one::1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one::CHEMBL239043

SMILES COCCn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O

InChI Key InChIKey=LTMJVVWUKDXQNB-UHFFFAOYSA-N

Data  8 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50200595   

TargetNociceptin receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  186nMAssay Description:Displacement of [3H]Diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  273nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  273nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  375nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Guinea pig)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  394nMAssay Description:Displacement of [3H]U-69593 from KOP receptor in guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Guinea pig)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  394nMAssay Description:Displacement of [3H]U-69593 from KOP receptor in guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  2.16E+3nMAssay Description:Displacement of [3H]naltrindole from human DOP receptor expressed in deltaC6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataIC50:  24nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataIC50:  24nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed