BDBM50200635 4-(6-(2-hydroxy-2-(methylamino)ethyl)naphthalen-2-yl)benzonitrile::CHEMBL246940

SMILES CNC(O)Cc1ccc2cc(ccc2c1)-c1ccc(cc1)C#N

InChI Key InChIKey=PTLOGEFRWHLLST-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200635   

TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200635(4-(6-(2-hydroxy-2-(methylamino)ethyl)naphthalen-2-...)
Affinity DataKi:  10.5nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200635(4-(6-(2-hydroxy-2-(methylamino)ethyl)naphthalen-2-...)
Affinity DataKi:  457nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed