BDBM50200648 (R)-4-(6-(2-(3-hydroxypyrrolidin-1-yl)ethyl)naphthalen-2-yl)benzonitrile::CHEMBL393899

SMILES O[C@@H]1CCN(CCc2ccc3cc(ccc3c2)-c2ccc(cc2)C#N)C1

InChI Key InChIKey=YHMZHAITUOKJPI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200648   

TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200648((R)-4-(6-(2-(3-hydroxypyrrolidin-1-yl)ethyl)naphth...)
Affinity DataKi:  1.56nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50200648((R)-4-(6-(2-(3-hydroxypyrrolidin-1-yl)ethyl)naphth...)
Affinity DataKi:  30.9nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed