BDBM50200819 CHEMBL3938021

SMILES COc1ccc(CNC(=O)N2[C@H](C)CN(Cc3ccc(o3)C(F)(F)F)c3cnccc3[C@@H]2C)cc1

InChI Key InChIKey=CNIBHFMXGCXGHJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50200819   

TargetVoltage-dependent T-type calcium channel subunit alpha-1I(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50200819(CHEMBL3938021)
Affinity DataIC50: 11nMAssay Description:Channel blocking activity at recombinant human CaV 3.3 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2018
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50200819(CHEMBL3938021)
Affinity DataIC50: 13nMAssay Description:Channel blocking activity at recombinant human CaV 3.1 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2018
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50200819(CHEMBL3938021)
Affinity DataIC50: 24nMAssay Description:Channel blocking activity at recombinant human CaV 3.2 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2018
Entry Details Article
PubMed