BDBM50201080 2-(benzoimidazol-1-ylmethyl)-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methylpentan-2-ol::CHEMBL373498

SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cn1cnc2ccccc12)C(F)(F)F

InChI Key InChIKey=JJSZJRHRVRGDNH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201080   

TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201080(2-(benzoimidazol-1-ylmethyl)-1,1,1-trifluoro-4-(5-...)
Affinity DataIC50: 54nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethasone binding to GR by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201080(2-(benzoimidazol-1-ylmethyl)-1,1,1-trifluoro-4-(5-...)
Affinity DataIC50: 775nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethasone binding to MR by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201080(2-(benzoimidazol-1-ylmethyl)-1,1,1-trifluoro-4-(5-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of tetramethylrhodamine labeled RU486 binding to PR by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed