BDBM50201086 CHEMBL216273::cis-1-[4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]-3,5-dimethylpiperidin-4-one

SMILES COc1ccc(F)cc1C(C)(C)CC(O)(CN1C[C@H](C)C(=O)[C@H](C)C1)C(F)(F)F

InChI Key InChIKey=FNAPHRONLYQVOG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201086   

TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201086(cis-1-[4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-me...)
Affinity DataIC50: 10nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethasone binding to GR by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201086(cis-1-[4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-me...)
Affinity DataIC50: 430nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethasone binding to MR by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201086(cis-1-[4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-me...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of tetramethylrhodamine labeled RU486 binding to PR by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed