BDBM50201102 1-(2-hydroxy-4-methyl-4-phenyl-2-(trifluoromethyl)pentyl)-1H-quinolin-4-one::CHEMBL219069

SMILES CC(C)(CC(O)(Cn1ccc(=O)c2ccccc12)C(F)(F)F)c1ccccc1

InChI Key InChIKey=LCTFQUGGLDHXTH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201102   

TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201102(1-(2-hydroxy-4-methyl-4-phenyl-2-(trifluoromethyl)...)
Affinity DataIC50: 28nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethasone binding to GR by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201102(1-(2-hydroxy-4-methyl-4-phenyl-2-(trifluoromethyl)...)
Affinity DataIC50: 106nMAssay Description:Inhibition of tetramethylrhodamine labeled RU486 binding to PR by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201102(1-(2-hydroxy-4-methyl-4-phenyl-2-(trifluoromethyl)...)
Affinity DataIC50: 350nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethasone binding to MR by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed