BDBM50201111 2-[(2,3-dihydrobenzo[1,4]oxazin-4-yl)methyl]-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methylpentan-2-ol::CHEMBL386915

SMILES COc1ccc(F)cc1C(C)(C)CC(O)(CN1CCOc2ccccc12)C(F)(F)F

InChI Key InChIKey=IDCRMONFSJJBMN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201111   

TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201111(2-[(2,3-dihydrobenzo[1,4]oxazin-4-yl)methyl]-1,1,1...)
Affinity DataIC50: 15nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethasone binding to GR by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201111(2-[(2,3-dihydrobenzo[1,4]oxazin-4-yl)methyl]-1,1,1...)
Affinity DataIC50: 310nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethasone binding to MR by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201111(2-[(2,3-dihydrobenzo[1,4]oxazin-4-yl)methyl]-1,1,1...)
Affinity DataIC50: 640nMAssay Description:Inhibition of tetramethylrhodamine labeled RU486 binding to PR by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed