BDBM50201223 2-((5S,6R)-2,4-dioxo-1,3-diaza-spiro[4.4]non-6-yl)-N-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-acetamide::CHEMBL247381::CHEMBL559170

SMILES Cc1cc(COc2ccc(NC(=O)C[C@H]3CCC[C@]33NC(=O)NC3=O)cc2)c2ccccc2n1

InChI Key InChIKey=WIITUDWGVPSKMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201223   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201223(CHEMBL247381 | CHEMBL559170 | 2-((5S,6R)-2,4-dioxo...)
Affinity DataIC50: 17nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201223(CHEMBL247381 | CHEMBL559170 | 2-((5S,6R)-2,4-dioxo...)
Affinity DataIC50: 900nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed