BDBM50201226 4-(2,4-dichloro-5-methoxyphenylamino)-6-methoxy-7-(4-(piperazin-1-yl)but-1-ynyl)quinoline-3-carbonitrile::CHEMBL240413

SMILES COc1cc(Nc2c(cnc3cc(C#CCCN4CCNCC4)c(OC)cc23)C#N)c(Cl)cc1Cl

InChI Key InChIKey=XPRRLPNUCNFQJO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201226   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201226(4-(2,4-dichloro-5-methoxyphenylamino)-6-methoxy-7-...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of Src activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201226(4-(2,4-dichloro-5-methoxyphenylamino)-6-methoxy-7-...)
Affinity DataIC50: 520nMAssay Description:Inhibition of Src in rat fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed