BDBM50201697 CHEMBL3943181

SMILES N[C@H]1CCCC[C@H]1Nc1cnc(C(N)=O)c(n1)-c1nc2ccccc2[nH]1

InChI Key InChIKey=LZQQEGBCKOIYIP-WDEREUQCSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50201697   

TargetTyrosine-protein kinase SYK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50201697(CHEMBL3943181)
Affinity DataIC50:  7nMAssay Description:Inhibition of GST-tagged full length human SYK (1 to 635 end residues) expressed in baculovirus expression system preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201697(CHEMBL3943181)
Affinity DataIC50:  420nMAssay Description:Inhibition of TSSK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50201697(CHEMBL3943181)
Affinity DataIC50:  130nMAssay Description:Inhibition of GST-tagged recombinant human LRRK2 (970 to 2527 residues) expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50201697(CHEMBL3943181)
Affinity DataIC50:  60nMAssay Description:Inhibition of His-tagged recombinant full length human CHK2 expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed