BDBM50202220 CHEMBL376787::bis(5-aminobenzo[b]furan-2-yl)methanone

SMILES Nc1ccc2oc(cc2c1)C(=O)c1cc2cc(N)ccc2o1

InChI Key InChIKey=UMBJVNBINWLZLH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202220   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50202220(bis(5-aminobenzo[b]furan-2-yl)methanone | CHEMBL37...)
Affinity DataIC50: 600nMAssay Description:Inhibition of endogenous FLT3 autophosphorylation in EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50202220(bis(5-aminobenzo[b]furan-2-yl)methanone | CHEMBL37...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of endogenous PDGFRbeta autophosphorylation in Swiss 3T3 fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed