BDBM50202760 4-(3-(1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)isoquinoline::CHEMBL391437

SMILES c1ccc2c(-c3cnc4[nH]nc(-c5nc6ccccc6[nH]5)c4c3)cncc2c1

InChI Key InChIKey=UBDAMLJKQGPQFB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50202760   

TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202760BDBM50202760(4-(3-(1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[3,4-b]...)
Affinity DataIC50: 23nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202760BDBM50202760(4-(3-(1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[3,4-b]...)
Affinity DataIC50: 140nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202760BDBM50202760(4-(3-(1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[3,4-b]...)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202760BDBM50202760(4-(3-(1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[3,4-b]...)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed