BDBM50203480 8-fluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-2H-benzo[e]isoindole-1,3-dione::CHEMBL243866

SMILES CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)N1C(=O)c2ccc3ccc(F)cc3c2C1=O

InChI Key InChIKey=QPJSKVVDVIYOKV-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50203480   

TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50203480(8-fluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-y...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [125]HEAT from human adrenergic alpha1d receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50203480(8-fluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-y...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [125]HEAT from human adrenergic alpha1d receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50203480(8-fluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-y...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [125]HEAT from human adrenergic alpha1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50203480(8-fluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-y...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [125]HEAT from human adrenergic alpha1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50203480(8-fluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-y...)
Affinity DataKi:  46.5nMAssay Description:Displacement of [125]HEAT from human adrenergic alpha1b receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50203480(8-fluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-y...)
Affinity DataKi:  46.5nMAssay Description:Displacement of [125]HEAT from human adrenergic alpha1b receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed