BDBM50203591 CHEMBL396821::[8-(2-chloro-4,6-dimethyl-phenyl)-2-methyl-8H-1,3a,7,8-tetraaza-cyclopenta[a]inden-3-ylmethyl]-methyl-(2-pyridin-2-yl-ethyl)-amine

SMILES CN(CCc1ccccn1)Cc1c(C)nc2n(-c3c(C)cc(C)cc3Cl)c3ncccc3n12

InChI Key InChIKey=IRWPFZHJKZQNRC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203591   

TargetCorticotropin-releasing factor receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50203591([8-(2-chloro-4,6-dimethyl-phenyl)-2-methyl-8H-1,3a...)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from CRF1 receptor expressed in IMR32 cells assessed as inhibition of CRF stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed