BDBM50203608 CHEMBL245671::cyclopropylmethyl-propyl-[2-trifluoromethyl-8-(2,4,6-trimethyl-phenyl)-8H-1,3a,7,8-tetraaza-cyclopenta[a]inden-3-ylmethyl]-amine

SMILES CCCN(CC1CC1)Cc1c(nc2n(-c3c(C)cc(C)cc3C)c3ncccc3n12)C(F)(F)F

InChI Key InChIKey=AZRZXCRQDGIRRE-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203608   

TargetCorticotropin-releasing factor receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50203608(cyclopropylmethyl-propyl-[2-trifluoromethyl-8-(2,4...)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]Tyr-o-CRF from CRF1 receptor expressed in IMR32 cells assessed as inhibition of CRF stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed