BDBM50203616 8-(2-chloro-4,6-dimethyl-phenyl)-2-methyl-3-(3-phenethyl-pyrrolidin-1-ylmethyl)-8H-1,3a,7,8-tetraaza-cyclopenta[a]indene::CHEMBL248163

SMILES Cc1nc2n(-c3c(C)cc(C)cc3Cl)c3ncccc3n2c1CN1CCC(CCc2ccccc2)C1

InChI Key InChIKey=PBEQQVOUDMAYFD-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203616   

TargetCorticotropin-releasing factor receptor 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50203616(8-(2-chloro-4,6-dimethyl-phenyl)-2-methyl-3-(3-phe...)
Affinity DataKi:  700nMAssay Description:Displacement of [125I]Tyr-o-CRF from CRF1 receptor expressed in IMR32 cells assessed as inhibition of CRF stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed