BDBM50203877 CHEMBL220652::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-2-phenylbutanamide

SMILES CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)C(CC)c2ccccc2)c2ccccc12

InChI Key InChIKey=QAELIZCZGHKYIN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203877   

TargetC-C chemokine receptor type 8(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203877(N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-...)
Affinity DataIC50: 7.65nMAssay Description:Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed