BDBM50203936 (S)-N-(3-methoxy-2-methylbenzyl)-N-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amine::CHEMBL247538

SMILES COc1cccc(CN([C@H]2CCNC2)C2CCOCC2)c1C

InChI Key InChIKey=IVMHSWRHRXAZNE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50203936   

LigandPNGBDBM50203936((S)-N-(3-methoxy-2-methylbenzyl)-N-(tetrahydro-2H-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]NA from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50203936((S)-N-(3-methoxy-2-methylbenzyl)-N-(tetrahydro-2H-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]5-HT from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50203936((S)-N-(3-methoxy-2-methylbenzyl)-N-(tetrahydro-2H-...)
Affinity DataIC50: 968nMAssay Description:Inhibition of [3H]DA from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50203936((S)-N-(3-methoxy-2-methylbenzyl)-N-(tetrahydro-2H-...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed