BDBM50204121 CHEMBL429827::N-(1-benzyl-1H-indazol-5-yl)-5-methylpyrrolo[1,2-f][1,2,4]triazin-4-amine

SMILES Cc1ccn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12

InChI Key InChIKey=QUMXZLSLZVWESB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204121   

TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204121(N-(1-benzyl-1H-indazol-5-yl)-5-methylpyrrolo[1,2-f...)
Affinity DataIC50: 86nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204121(N-(1-benzyl-1H-indazol-5-yl)-5-methylpyrrolo[1,2-f...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant cytoplasmic HER2 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed