BDBM50204132 5-(((S)-morpholin-2-ylmethoxy)methyl)-N-(1-((R)-1-phenylethyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine::CHEMBL394495

SMILES C[C@H](c1ccccc1)n1ncc2cc(Nc3ncnn4ccc(COC[C@@H]5CNCCO5)c34)ccc12

InChI Key InChIKey=CJHNARCORXPMOD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204132   

TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204132(5-(((S)-morpholin-2-ylmethoxy)methyl)-N-(1-((R)-1-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204132(5-(((S)-morpholin-2-ylmethoxy)methyl)-N-(1-((R)-1-...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant cytoplasmic HER2 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed