BDBM50204399 (3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)methyl)benzamido)-tetrahydrofuran-3-carboxamide::CHEMBL234033

SMILES Cc1cc(Cc2cccc(c2)C(=O)N[C@@H]2COC[C@@H]2C(=O)NO)c2ccccc2n1

InChI Key InChIKey=UNCGRKPTWVECFJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50204399   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204399((3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)met...)
Affinity DataIC50: 2nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204399((3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)met...)
Affinity DataIC50: 130nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204399((3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)met...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204399((3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)met...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204399((3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)met...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204399((3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)met...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed