BDBM50204673 CHEMBL3927929

SMILES COc1ccccc1N1CCN(Cc2cc3OCOc3c(c2)-c2ccccc2OC)CC1

InChI Key InChIKey=GWZQOWNCFVYXHK-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50204673   

Target5-hydroxytryptamine receptor 7(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50204673(CHEMBL3927929)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50204673(CHEMBL3927929)
Affinity DataIC50: 1.98E+4nMAssay Description:Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50204673(CHEMBL3927929)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2018
Entry Details Article
PubMed