BDBM50204772 8-(6,7-dichloro-4,4-dimethyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL393980

SMILES CC1(C)CCC(N2CCC3(CC2)N(CNC3=O)c2ccccc2)c2cc(Cl)c(Cl)cc12

InChI Key InChIKey=GAXICRLQZFWIKP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50204772   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204772(8-(6,7-dichloro-4,4-dimethyl-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204772(8-(6,7-dichloro-4,4-dimethyl-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  938nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204772(8-(6,7-dichloro-4,4-dimethyl-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  977nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204772(8-(6,7-dichloro-4,4-dimethyl-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  1.17E+4nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed