BDBM50204773 8-[bis-(2-fluoro-phenyl)-methyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL239820

SMILES Fc1ccccc1C(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1F

InChI Key InChIKey=GPNRKVNAMNPYNQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50204773   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204773(8-[bis-(2-fluoro-phenyl)-methyl]-1-phenyl-1,3,8-tr...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204773(8-[bis-(2-fluoro-phenyl)-methyl]-1-phenyl-1,3,8-tr...)
Affinity DataKi:  567nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204773(8-[bis-(2-fluoro-phenyl)-methyl]-1-phenyl-1,3,8-tr...)
Affinity DataKi:  858nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204773(8-[bis-(2-fluoro-phenyl)-methyl]-1-phenyl-1,3,8-tr...)
Affinity DataKi:  1.60E+4nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed