BDBM50204883 (6-hydroxy-1H-benzimidazol-2-yl)-(4-p-tolyloxy-piperidin-1-yl]-methanone::CHEMBL219986

SMILES Cc1ccc(OC2CCN(CC2)C(=O)c2nc3cc(O)c(O)cc3[nH]2)cc1

InChI Key InChIKey=SVAOEAMMJVHVKK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204883   

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50204883((6-hydroxy-1H-benzimidazol-2-yl)-(4-p-tolyloxy-pip...)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50204883((6-hydroxy-1H-benzimidazol-2-yl)-(4-p-tolyloxy-pip...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed