BDBM50205683 1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylethyl)-1-methyl-3-(2-oxo-2-(phenylamino)ethyl)urea::CHEMBL230502

SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)NCC(=O)Nc1ccccc1

InChI Key InChIKey=WSFQCNYXQWFYJC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50205683   

TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205683(1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylet...)
Affinity DataKi:  6.5nMAssay Description:Agonist activity at human kappa opioid receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205683(1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylet...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed