BDBM50205806 CHEMBL3969839

SMILES Oc1cc2O\C(=C/c3ccc(=O)n(O)c3)C(=O)c2c(O)c1

InChI Key InChIKey=PVVQBJMLBJRPGS-UHFFFAOYSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50205806   

TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50205806(CHEMBL3969839)
Affinity DataKi:  1.20E+3nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50205806(CHEMBL3969839)
Affinity DataKi:  1.20E+3nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50205806(CHEMBL3969839)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells assessed as diphenolase activity using L-DOPA as substrate by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)TBA
LigandPNGBDBM50205806(CHEMBL3969839)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to mushroom Tyrosinase using L-DOPA as substrate assessed as inhibition constant by Michaelis-Menten analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50205806(CHEMBL3969839)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50205806(CHEMBL3969839)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50205806(CHEMBL3969839)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of tyrosinase in human MNT1 cell lysate pretreated prior to addition of L-DOPA as substrate measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed
TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50205806(CHEMBL3969839)
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of tyrosinase in human MNT1 cells assessed as suppression of melanin biosynthesis measured after 96 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed