BDBM50206038 ((2S,4S)-4-(4-(4-nitrophenyl)piperazin-1-yl)pyrrolidin-2-yl)(thiazolidin-3-yl)methanone::CHEMBL391466

SMILES [O-][N+](=O)c1ccc(cc1)N1CCN(CC1)[C@@H]1CN[C@@H](C1)C(=O)N1CCSC1

InChI Key InChIKey=ZHJLERMYNKCYGH-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50206038   

TargetDipeptidyl peptidase 4(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50206038(((2S,4S)-4-(4-(4-nitrophenyl)piperazin-1-yl)pyrrol...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human DPP4 using Gly-Pro-MCA as substrate after 60 mins by fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50206038(((2S,4S)-4-(4-(4-nitrophenyl)piperazin-1-yl)pyrrol...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50206038(((2S,4S)-4-(4-(4-nitrophenyl)piperazin-1-yl)pyrrol...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of DPP4 in human plasma using GLY-Pro-MCA as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50206038(((2S,4S)-4-(4-(4-nitrophenyl)piperazin-1-yl)pyrrol...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of DPP4 in rat plasma by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50206038(((2S,4S)-4-(4-(4-nitrophenyl)piperazin-1-yl)pyrrol...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human DPP8 using GLY-Pro-MCA as substrate after 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50206038(((2S,4S)-4-(4-(4-nitrophenyl)piperazin-1-yl)pyrrol...)
Affinity DataIC50: 12.2nMAssay Description:Inhibition of human recombinant DPP8 using Gly-Pro-MCA as substrate after 30 mins by fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50206038(((2S,4S)-4-(4-(4-nitrophenyl)piperazin-1-yl)pyrrol...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human DPP9 using GLY-Pro-MCA as substrate after 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50206038(((2S,4S)-4-(4-(4-nitrophenyl)piperazin-1-yl)pyrrol...)
Affinity DataIC50: 30.2nMAssay Description:Inhibition of human recombinant DPP9 using Gly-Pro-MCA as substrate after 30 mins by fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed