BDBM50206275 5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(thiophen-2-yl)pyrimidin-2-amine::CHEMBL233380

SMILES CN(C)CCc1ccc(Nc2ncc(Cl)c(n2)-c2cccs2)cc1

InChI Key InChIKey=SXGDTPHXBFVMQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206275   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206275(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(t...)
Affinity DataIC50: 159nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206275(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(t...)
Affinity DataIC50: 461nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed