BDBM50206282 5-chloro-4-(1H-indol-3-yl)-N-(4-(2-(4-methylpiperazin-1-yl)ethyl)phenyl)pyrimidin-2-amine::CHEMBL233224

SMILES CN1CCN(CCc2ccc(Nc3ncc(Cl)c(n3)-c3c[nH]c4ccccc34)cc2)CC1

InChI Key InChIKey=GFMLSFXYFKGRNS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206282   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206282(5-chloro-4-(1H-indol-3-yl)-N-(4-(2-(4-methylpipera...)
Affinity DataIC50:  7nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206282(5-chloro-4-(1H-indol-3-yl)-N-(4-(2-(4-methylpipera...)
Affinity DataIC50:  180nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed