BDBM50206927 3-{4-[1-(4-(aminosulfonyl)phenyl)-4-chloro-1H-imidazol-5-yl]-2-fluorophenoxy}propyl Nitrate::CHEMBL376246

SMILES NS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1ccc(OCCCO[N+]([O-])=O)c(F)c1

InChI Key InChIKey=AYVOAOGOGQOXHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206927   

TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206927(3-{4-[1-(4-(aminosulfonyl)phenyl)-4-chloro-1H-imid...)
Affinity DataIC50: 1.60E+4nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206927(3-{4-[1-(4-(aminosulfonyl)phenyl)-4-chloro-1H-imid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as TxB2 production after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed