BDBM50206928 3-{4-[4-chloro-1-(4-(methylsulfonyl)phenyl)-1H-imidazol-5-yl]-2-fluorophenoxy}propyl Nitrate::CHEMBL373819

SMILES CS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1ccc(OCCCO[N+]([O-])=O)c(F)c1

InChI Key InChIKey=CKGUNXIOZYDUPF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206928   

TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206928(3-{4-[4-chloro-1-(4-(methylsulfonyl)phenyl)-1H-imi...)
Affinity DataIC50: 1.40E+4nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206928(3-{4-[4-chloro-1-(4-(methylsulfonyl)phenyl)-1H-imi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as TxB2 production after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed