BDBM50207767 CHEMBL245509::adamantan-1-yl-[4-(2-hydroxy-ethyl)-piperazin-1-yl]-methanone

SMILES OCCN1CCN(CC1)C(=O)C12CC3CC(CC(C3)C1)C2

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207767   

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207767(adamantan-1-yl-[4-(2-hydroxy-ethyl)-piperazin-1-yl...)
Affinity DataIC50: 494nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207767(adamantan-1-yl-[4-(2-hydroxy-ethyl)-piperazin-1-yl...)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed