BDBM50207863 3-isopropyl-N-(3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)-5-(trifluoromethyl)phenyl)benzamide::CHEMBL245949

SMILES CNc1ncnc(n1)-c1cccnc1Oc1cc(NC(=O)c2cccc(c2)C(C)C)cc(c1)C(F)(F)F

InChI Key InChIKey=KHYNXSBMNXFETH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207863   

TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50207863(3-isopropyl-N-(3-(3-(4-(methylamino)-1,3,5-triazin...)
Affinity DataIC50: 55nMAssay Description:Inhibition of Tie2 after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50207863(3-isopropyl-N-(3-(3-(4-(methylamino)-1,3,5-triazin...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KDR after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed