BDBM50207950 1-(2-(4-(4-(4-fluorophenyl)piperazin-1-yl)butoxy)phenyl)-3-phenylpropan-1-one::CHEMBL222276

SMILES Fc1ccc(cc1)N1CCN(CCCCOc2ccccc2C(=O)CCc2ccccc2)CC1

InChI Key InChIKey=WJYNUACBELMVND-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207950   

TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandPNGBDBM50207950(1-(2-(4-(4-(4-fluorophenyl)piperazin-1-yl)butoxy)p...)
Affinity DataEC50:  192nMAssay Description:Inhibition of P-glycoprotein expressed in MDR CCRF vcr1000 cells by daunorubicin efflux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed