BDBM50208149 CHEMBL3937916::US9708270, 11

SMILES CC1(C)Cc2cc(Cl)cc(N3CCC4(CCC(CC(O)=O)CC4)CC3)c2O1

InChI Key InChIKey=NUGWEZBZPNGBKL-UHFFFAOYSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50208149   

TargetFree fatty acid receptor 4(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50208149(CHEMBL3937916 | US9708270, 11)
Affinity DataEC50:  670nMAssay Description:Agonist activity at mouse GPR120 expressed in CHOK1 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50208149(CHEMBL3937916 | US9708270, 11)
Affinity DataEC50:  670nMAssay Description:Agonist activity at mouse GPR120 expressed in CHOK1 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208149(CHEMBL3937916 | US9708270, 11)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50208149(CHEMBL3937916 | US9708270, 11)
Affinity DataEC50:  2.85E+3nMAssay Description:On the day before the measurement day, CHO cells expressing human GPR120 were plated at 10000 cells per well in a 384-well black plate (#3702, Cornin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50208149(CHEMBL3937916 | US9708270, 11)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at ARMS2-PK2 -tagged human GPR120 short isoform expressed in CHOK1 cells assessed as induction of beta-arrestin2 recruitment after 9...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50208149(CHEMBL3937916 | US9708270, 11)
Affinity DataEC50:  4.00E+3nMAssay Description:Agonist activity at mouse GPR120 expressed in U2OS cells assessed as induction of beta-arrestin2 recruitment after 90 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50208149(CHEMBL3937916 | US9708270, 11)
Affinity DataEC50:  3.30E+3nMAssay Description:Agonist activity at human GPR120 short isoform expressed in CHOK1 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed